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[89Zr]-oxine-NCR100

Development stage: Unknown
Lead developer: Nuwacell Biotechnologies
Modality: Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Local (intra-articular)

Overview

**[89Zr]-oxine-NCR100** is a radiolabeled diagnostic agent consisting of the radioactive isotope zirconium-89 (^89Zr) complexed with oxine (8-hydroxyquinoline), specifically formulated in the product *NCR100*, and is intended for in vivo cell-tracking and biodistribution studies using PET/CT imaging. The compound allows non-invasive tracking of cell therapies or labeled cell populations by enabling visualization of their distribution and kinetics in the body over time post-injection. It is currently being evaluated for the cellular distribution after local injection in knee osteoarthritis, with the main goal of quantifying uptake and organ distribution of labeled cells, providing real-time insight on cell therapy biodistribution[1][3][5].

Other names: [89Zr]-Oxine-NCR100 injection

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